Canadian Society for Medical Laboratory Science (CSMLS) Practice Exam

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Which cells play the most significant role in blood clotting?

Lymphocytes
RBC
Platelets
WBC

The correct answer is: Platelets

Platelets, also known as thrombocytes, play a crucial role in the blood clotting process. When an injury occurs to a blood vessel, platelets are activated and adhere to the site of injury. They aggregate together to form a temporary "platelet plug" to help stop bleeding. Additionally, platelets release various substances that promote the coagulation process, which is essential for forming a stable clot. This process is part of hemostasis, where platelets work in conjunction with clotting factors and other components of the blood to ensure that bleeding is effectively controlled. The unique function of platelets makes them the primary cellular component in the clotting mechanism, distinguishing them from other blood cells like RBCs, which are primarily responsible for oxygen transport, and WBCs, which are involved in the immune response. Lymphocytes also play roles in immunity and do not participate in blood clotting.